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Keshu

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Tuberculosis

🦠 What is Tuberculosis?

TB is a contagious infection caused by the bacterium Mycobacterium tuberculosis. It primarily attacks the lungs (pulmonary TB), but it can also spread to other parts of the body, such as the kidneys, spine, and brain (extrapulmonary TB).

How it Spreads

TB is airborne. When a person with active pulmonary TB coughs, sneezes, or speaks, they release microscopic droplets containing the bacteria into the air. If another person inhales these droplets, they can become infected.

🩺 Latent vs. Active TB

Not everyone infected with TB bacteria becomes sick. There are two distinct stages:

  1. Latent TB Infection: The bacteria remain in the body in an inactive state. You have no symptoms and cannot spread the disease to others. however, the bacteria can "wake up" later if the immune system weakens.

  2. Active TB Disease: The bacteria multiply and cause illness. In this stage, you can spread the disease to others.

🚩 Common Symptoms

If the infection becomes active in the lungs, symptoms typically include:

  • A persistent cough lasting 3 weeks or longer.

  • Coughing up blood or sputum (phlegm).

  • Chest pain.

  • Unexplained weight loss and loss of appetite.

  • Night sweats and fever.

  • General fatigue.

🏛️ Why was it called "The White Death"?

In the 18th and 19th centuries, TB reached epidemic proportions in Europe and North America. It earned its grim nickname because:

  • Pallor: Patients became extremely pale and thin (hence "the Great White Plague").

  • Consumption: The disease seemed to "consume" the body from the inside out.

  • Romanticism: Interestingly, during the Victorian era, the "tubercular look" was briefly romanticized in art and literature as a sign of sensitivity and beauty, before the germ theory of disease was fully understood.

  • Getty Images

💊 Treatment and Prevention

The discovery of Streptomycin in 1943 changed everything, turning a death sentence into a curable condition.

  • Treatment: Modern TB is treated with a combination of antibiotics taken over 6 to 9 months. It is crucial to finish the entire course to prevent Multi-Drug Resistant TB (MDR-TB).

  • Vaccination: The BCG vaccine is often given to children in countries where TB is common, though its effectiveness in adults varies.

  • Testing: Skin tests (Mantoux) or blood tests (IGRA) can determine if you have been exposed to the bacteria.

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