What Is the Cell Membrane?
The cell membrane is the outer covering of the cell.
It protects the cell and controls what enters and exits.
It is found in all cells – both animal and plant cells.
It is selectively permeable, which means it allows some substances to pass through but blocks others.
What Is the Cell Membrane Made Of?
Phospholipid Bilayer
The main part of the membrane is a double layer of phospholipids.
Each phospholipid has a water-loving head and water-hating tails.
The heads face the water inside and outside the cell, the tails hide inside, away from water.
This structure gives the membrane its flexibility and makes it a good barrier.
Proteins
• Integral proteins go across the membrane.
They form channels or transporters to move substances in and out.
• Peripheral proteins are on the surface of the membrane.
They help the cell communicate and support its structure.
• Some proteins act as receptors, which receive signals from outside the cell.
Integral Proteins
Found inside the membrane, often going all the way through.
Help with transport of substances and act as receptors for signals.
Peripheral Proteins
Found on the surface of the membrane, not inside it.
Help with cell shape, support, and communication.
3. Cholesterol
• Found in animal cell membranes (not plant cells).
• It makes the membrane stronger and less fluid, helping it stay stable in different temperatures.
4. Carbohydrates
• Attached to proteins (glycoproteins) or lipids (glycolipids).
• These are used for cell recognition, cell signaling, and helping cells stick to one another.
What Does the Cell Membrane Do?
• Protects the cell and holds its shape.
• Controls what enters and leaves (nutrients, water, waste, gases).
• Allows communication with other cells using receptors.
• Helps the cell respond to changes in its surroundings.
• Supports cell attachment to other cells or surfaces.
Note/summary- These are the 5 things inside a cell membrane:
Phospholipids – form the basic double layer (bilayer).
Integral Proteins – go through the membrane; help with transport and signals.
Peripheral Proteins – sit on the surface; help with structure and communication.
Cholesterol – adds strength and flexibility (in animal cells).
Carbohydrates – attached to proteins or lipids; help with cell recognition.
How could you design an experiment to measure the permeability of a cell membrane?
What techniques are used to study membrane proteins, and what are their limitations?
How would altering the temperature affect membrane fluidity and transport?
What modern tools allow visualization of membrane dynamics in living cells?
How do viruses exploit the cell membrane to enter host cells?
How do differences in membrane composition relate to drug resistance in cancer cells?
Can artificial membranes be used to create synthetic cells? What are the challenges?
keywords
Cell membrane (plasma membrane)
Phospholipid bilayer
Hydrophilic head
Hydrophobic tail
Fluid mosaic model
Cholesterol
Lipid bilayer
Membrane proteins
Integral proteins
Peripheral proteins
Selective permeability
Passive transport
Active transport
Diffusion
Osmosis
Facilitated diffusion
Carrier proteins
Channel proteins
Endocytosis
Exocytosis